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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IL1RN, interleukin 1 receptor antagonist
Sequence ID:NM_000577
NM_173841
NM_173842
NM_173843
RefSeqGene ID:NG_021240
Entrez Gene ID:3557
Ensembl ID:ENSG00000136689

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GASTRIC CANCER RISK AFTER H. PYLORI INFECTIONAPC
APC
CASP10
CDH1
ERBB2
FGFR2
IL1B
IRF1
KLF6
KLF6
KRAS
MUTYH
PIK3CA
PIK3CA
INTERLEUKIN 1 RECEPTOR ANTAGONIST DEFICIENCY 
MICROVASCULAR COMPLICATIONS OF DIABETES 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q14.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 113875469 - 113890448

 Exon Info From UCSC:
NM_000577
NM_173841
NM_173842
NM_173843

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3689284Full LengthBC009745interleukin 1 receptor antagonist
5270437IncompleteBC068441interleukin 1 receptor antagonist

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_776214  NP_776213  NP_000568  NP_776215  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000577 NP_000568   IL1
NM_173841 NP_776213   IL1
NM_173842 NP_776214 P18510 IL1
NM_173843 NP_776215   IL1

Related Sequences

 
mRNAGenPeptSwissProt
M55646 AAA59138 P18510
AF043143 AAC39672 P18510
BC009745 AAH09745 P18510
DQ892566 ABM83492  
DQ895781 ABM86707  
AK290898 BAF83587 P18510
AK290926 BAF83615 P18510
AJ005835 CAA06730  
X52015 CAA36262 P18510
X53296 CAA37386 P18510
X84348 CAA59087 P18510

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL1RN NP_776214 M.musculus Il1rn 16181 Gene Info NP_001034790 76
R.norvegicus Il1rn 60582   NP_071530 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta