Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. UCP2, uncoupling protein 2 (mitochondrial, proton carrier)
Sequence ID:NM_003355
RefSeqGene ID:NG_011478
Entrez Gene ID:7351
Ensembl ID:ENSG00000175567

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
OBESITYADRB2
ADRB3
AGRP
CARTPT
ENPP1
FTO
GHRL
MC3R
MC4R
NR0B2
POMC
PPARG
PPARGC1B
PYY
SDC3
SIM1
UCP1
UCP3
UCP3

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 73685711 - 73694352

NM_003355 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
14517368571573686165
4526327368653573686715
6337347368768573687786
7359297368786773688061
93011407368893073689140
114113657368929773689521
136615227369252073692676
152316467369376573693888

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4335185Full LengthBC011737uncoupling protein 2 (mitochondrial, proton carrier)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003346  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003355 NP_003346 P55851 Mito_carr

Related Sequences

 
mRNAGenPeptSwissProt
U76367 AAB48411 P55851
U82819 AAC51336 P55851
BC011737 AAH11737 P55851
DQ893298 ABM84224  
DQ896736 ABM87735  
AK222540 BAD96260 P55851
AK222557 BAD96277 P55851

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens UCP2 NP_003346 M.musculus Ucp2 22228 Gene Info NP_035801 96
R.norvegicus Ucp2 54315   NP_062227 95
A.gambiae AgaP_AGAP011676 1280964   XP_552584 63
A.thaliana PUMP1 824578   NP_190979 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)