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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. STAT4, signal transducer and activator of transcription 4
Sequence ID:NM_001243835
NM_003151
RefSeqGene ID:NG_012852
Entrez Gene ID:6775
Ensembl ID:ENSG00000138378

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
?SYSTEMIC LUPUS ERYTHEMATOSUS, OR PROTECTION AGAINSTBANK1
C4A
C4A
DNASE1
DNASE1
FASLG
FCGR2B
FCGR3A
ITGAX
PDCD1
PTPN22
TREX1
TREX1
TREX1
RHEUMATOID ARTHRITISCD244
CIITA
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL10
NFKBIL1
PADI4
PTPN22
RUNX1
RUNX1
SLC22A4

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q32.2-q32.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 191896851 - 191923480


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4830583Full LengthBC031212signal transducer and activator of transcription 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003142  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001243835 NP_001230764    
NM_003151 NP_003142 Q14765 SH2
STAT_alpha
STAT_bind
STAT_int

Related Sequences

 
mRNAGenPeptSwissProt
L78440 AAB05605 Q14765
BC031212 AAH31212 Q14765
DQ891548 ABM82474  
DQ894736 ABM85662  
EU304788 ACA01857 Q53RU2
EU304789 ACA01858 Q53RU2
EU304790 ACA01859 B7SIX5
EU304791 ACA01860 B7SIX5
EU304792 ACA01861 Q53RU2
EU304793 ACA01862 Q53RU2
AB209043 BAD92280 Q59GR6
AK299976 BAG61799 B4DSY7
AK300868 BAG62516 B4DV04
AK301172 BAG62759 B4DVP7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens STAT4 NP_003142 M.musculus Stat4 20849 Gene Info NP_035617 95
R.norvegicus Stat4 367264   NP_001012226 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta