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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. POLR2C, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Sequence ID:NM_032940
NM_002694
Entrez Gene ID:5432
Ensembl ID:ENSG00000102978

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q13-q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 57496636 - 57505036

Transcript StartTranscript EndChromosomal Start Chromosomal End
11725749655057496721
1732225749694057496989
2232915749986457499932
2923445750008657500138
3454735750307657503204
4745255750362157503672
5266945750387257504040
6957695750419157504265
77018045750488657505920

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2957867Full LengthBC003159polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
2960943Full LengthBC000409polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
5240953Full LengthBC028157polymerase (RNA) II (DNA directed) polypeptide C, 33kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_116558  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_032940 NP_116558 Q6FGR6
P19387
RNA_pol_A_bac
RNA_pol_L

Related Sequences

 
mRNAGenPeptSwissProt
J05448 AAA36586 P19387
AF008443 AAC14355 Q6FGR6
P19387
BC000409 AAH00409 Q6FGR6
P19387
BC003159 AAH03159 Q6FGR6
P19387
BC028157 AAH28157 Q6FGR6
P19387
DQ891411 ABM82337  
DQ894586 ABM85512  
EU176305 ABW03756  
AK293112 BAF85801 Q6FGR6
AK300124 BAH13217 B7Z6D1
AJ224143 CAA11842 P19387
AJ224144 CAA11843 P19387
CR542041 CAG46838 Q6FGR6
P19387

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLR2C NP_116558 M.musculus Polr2c 20021 Gene Info NP_033116 99
R.norvegicus Polr2c 361365   NP_001012491 99
A.gambiae AgaP_AGAP010321 1278625   XP_318245 71
D.melanogaster RpII33 34796   NP_477419 69
C.elegans rpb-3 172680   NP_492361 58
N.crassa NCU01515 3873127   XP_956964 50
A.thaliana NRPB3 816035   NP_179145 48
S.pombe rpb3 2538816   NP_588324 48
S.cerevisiae RPB3 854791   NP_012243 47
A.thaliana NRPE3B 816032   NP_179142 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)