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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PCSK1, Proprotein convertase subtilisin/kexin type 1
Sequence ID:NM_000439
NM_001177875
NM_001177876
RefSeqGene ID:NG_021161
Entrez Gene ID:5122
Ensembl ID:ENSG00000175426

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:5q15-q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 95726068 - 95768661

 Exon Info From UCSC:
NM_000439
NM_001177875
NM_001177876

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020475Full LengthBC136486proprotein convertase subtilisin/kexin type 1
40146326Full LengthBC130295proprotein convertase subtilisin/kexin type 1
5275840IncompleteBC031211proprotein convertase subtilisin/kexin type 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000430  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000439 NP_000430 P29120 EC 3.4.21.93 Peptidase_S8
P_proprotein
NM_001177875 NP_001171346      
NM_001177876 NP_001171347      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M90753 AAA59918 P29120 EC 3.4.21.93
BC130295 AAI30296 A1L3V6  
BC136486 AAI36487 A1L3V6  
AB208874 BAD92111 Q59H85  
AK303888 BAH14073 B7Z8T7  
X64810 CAA46031 P29120 EC 3.4.21.93

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PCSK1 NP_000430 M.musculus Pcsk1 18548 Gene Info NP_038656 93
R.norvegicus Pcsk1 25204   NP_058787 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)