Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TIE1, tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Sequence ID:NM_001253357
NM_005424
RefSeqGene ID:NG_030673
Entrez Gene ID:7075
Ensembl ID:ENSG00000066056

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34-p33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 43766689 - 43788779


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5767075Full LengthBC038239tyrosine kinase with immunoglobulin-like and EGF-like domains 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005415  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001253357 NP_001240286      
NM_005424 NP_005415 P35590 EC 2.7.10.1 EGF
fn3
ig
Pkinase_Tyr
EGF_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF217976 AAG17219 Q9HBS4  
BC038239 AAH38239 P35590 EC 2.7.10.1
EU826586 ACF47622 B5A948  
EU826587 ACF47623 B5A949  
EU826588 ACF47624 B5A950  
EU826589 ACF47625 B5A951  
EU826590 ACF47626 B5A952  
AK296735 BAG59322 B4DKW0  
AK300399 BAG62130 B4DTW8  
AK300623 BAG62316 B4DUF4  
X60957 CAA43290 P35590 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TIE1 NP_005415 M.musculus Tie1 21846 Gene Info NP_035717 93
R.norvegicus Tie1 89806   NP_445997 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)