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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. UROD, uroporphyrinogen decarboxylase
Sequence ID:NM_000374
RefSeqGene ID:NG_007122
Entrez Gene ID:7389
Ensembl ID:ENSG00000126088

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 45477919 - 45481341

NM_000374 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542421Full LengthBC001778uroporphyrinogen decarboxylase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000365  

Protein Infomation

NM_000374 NP_000365 P06132 EC URO-D

Related Sequences

M14016 AAA61258 P06132 EC
AF104421 AAD04571 P06132 EC
AF104422 AAD04572 P06132 EC
AF104423 AAD04573 P06132 EC
AF104424 AAD04574 P06132 EC
AF104425 AAD04575 P06132 EC
AF104426 AAD04576 P06132 EC
AF104427 AAD04577 P06132 EC
AF104428 AAD04578 P06132 EC
AF104429 AAD04579 P06132 EC
AF104430 AAD04580 P06132 EC
AF104431 AAD04581 P06132 EC
AF104432 AAD04582 P06132 EC
AF104433 AAD04583 P06132 EC
AF104434 AAD04584 P06132 EC
AF104435 AAD04585 P06132 EC
AF104436 AAD04586 P06132 EC
AF104437 AAD04587 P06132 EC
AF104438 AAD04588 P06132 EC
AF104439 AAD04589 P06132 EC
AF104440 AAD04590 P06132 EC
BC001778 AAH01778 P06132 EC
BT006737 AAP35383 P06132 EC
DQ890688 ABM81614    
DQ893870 ABM84796    
AK291877 BAF84566 P06132 EC
AK315878 BAF98769 B0AZT7  
AK293702 BAG57136 B4DEM5  
AK295284 BAG58268 B4DHV6  
CR456976 CAG33257 P06132 EC
CR542057 CAG46854 P06132 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens UROD NP_000365 M.musculus Urod 22275 Gene Info NP_033504 93
R.norvegicus Urod 29421   NP_062082 93
A.gambiae AgaP_AGAP011895 1280765   XP_320631 57
D.melanogaster Updo 35986   NP_001137627 55
S.pombe hem12 2539032   NP_588085 54
S.cerevisiae HEM12 851617   NP_010332 53
N.crassa NCU02771 3880415   XP_964266 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta