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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PNKP, polynucleotide kinase 3'-phosphatase
Sequence ID:NM_007254
RefSeqGene ID:NG_027717
Entrez Gene ID:11284
Ensembl ID:ENSG00000039650

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 10 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.3-q13.4Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 50364462 - 50370800

 Exon Info From UCSC:
NM_007254

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3140712Full LengthBC002519polynucleotide kinase 3'-phosphatase
5218400Full LengthBC033822polynucleotide kinase 3'-phosphatase
3535537IncompleteBC013034polynucleotide kinase 3'-phosphatase
4128572IncompleteBC009339polynucleotide kinase 3'-phosphatase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009185  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_007254 NP_009185 Q96T60 EC 3.1.3.32
EC 2.7.1.78
PNK3P

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF120499 AAD47379 Q96T60 EC 3.1.3.32
EC 2.7.1.78
AF125807 AAD50639 Q96T60 EC 3.1.3.32
EC 2.7.1.78
AF126486 AAD51135 Q96T60 EC 3.1.3.32
EC 2.7.1.78
BC002519 AAH02519 Q9BUL2  
BC033822 AAH33822 Q96T60 EC 3.1.3.32
EC 2.7.1.78
DQ890806 ABM81732    
DQ893961 ABM84887    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PNKP NP_009185 R.norvegicus Pnkp 308576   NP_001004259 82
M.musculus Pnkp 59047 Gene Info NP_067524 81
C.elegans F21D5.5 177681   NP_501503 46
D.melanogaster CG9601 40994   NP_649792 42
N.crassa NCU08151 3875713   XP_959562 41
S.pombe pnk1 2542032   NP_593635 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)