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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CSK, c-src tyrosine kinase
Sequence ID:NM_001127190
NM_004383
Entrez Gene ID:1445
Ensembl ID:ENSG00000103653

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:15q24.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 75090638 - 75094852

 Exon Info From UCSC:
NM_001127190
NM_004383

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6526810Full LengthBC106073c-src tyrosine kinase
8143850Full LengthBC104847c-src tyrosine kinase
8143878Full LengthBC104875c-src tyrosine kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004374  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001127190 NP_001120662      
NM_004383 NP_004374 P41240 EC 2.7.10.2 SH2
SH3_1
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC104847 AAI04848 P41240 EC 2.7.10.2
BC104875 AAI04876 P41240 EC 2.7.10.2
BC106073 AAI06074 P41240 EC 2.7.10.2
AK223626 BAD97346 Q53EL3  
AK290531 BAF83220 A8K3B6  
AK312669 BAG35551 B2R6Q4  
AK127672 BAG54548 B2R6Q4  
AK297694 BAG60052 B4DMZ0  
AK298245 BAG60511 B4DP99  
AB451288 BAG70102 B5BU52  
AB451420 BAG70234 B5BU52  
X59932 CAA42556 P41240 EC 2.7.10.2
X60114 CAA42713 P41240 EC 2.7.10.2
CR541960 CAG46758 P41240 EC 2.7.10.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CSK NP_001120662 M.musculus Csk 12988 Gene Info NP_031809 99
R.norvegicus Csk 315707   NP_001025210 98
D.melanogaster Csk 41398   NP_788638 63
A.gambiae AgaP_AGAP003986 1278803   XP_318436 61
C.elegans csk-1 266817   NP_001021778 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta