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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PAFAH1B1, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Sequence ID:NM_000430
RefSeqGene ID:NG_009799
Entrez Gene ID:5048
Ensembl ID:ENSG00000007168

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LISSENCEPHALY 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 2541582 - 2585096

 Exon Info From UCSC:
NM_000430

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5786560Full LengthBC064638platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000421  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000430 NP_000421 P43034 WD40
LisH

Related Sequences

 
mRNAGenPeptSwissProt
L13385 AAA02880 P43034
L13386 AAA02881 P43034
L13387 AAA02882 P43034
BC064638 AAH64638 P43034
AF400434 AAK92483 P43034
AF208837 AAL34972 P43034
AF208838 AAL34973 P43034
AK313078 BAG35904 P43034
AK293918 BAG57299 B4DF38
AK303015 BAG64145 B4DZN3
BX538346 CAD98141 P43034

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAFAH1B1 NP_000421 M.musculus Pafah1b1 18472 Gene Info NP_038653 100
R.norvegicus Pafah1b1 83572   NP_113951 100
A.gambiae AgaP_AGAP011849 1280803   XP_320670 72
D.melanogaster Lis-1 36791   NP_788370 71
C.elegans lis-1 176758   NP_499755 59
N.crassa NCU04534 3873083   XP_956945 51
N.crassa NCU04312 3877099   XP_960958 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta