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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PLAU, plasminogen activator, urokinase
Sequence ID:NM_001145031
NM_002658
RefSeqGene ID:NG_011904
Entrez Gene ID:5328
Ensembl ID:ENSG00000122861

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALZHEIMER DISEASEA2M
ACE
APBB2
APP
BLMH
HFE
MPO
NOS3
PAXIP1
SORL1
QUEBEC PLATELET DISORDER 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 75673346 - 75677256

 Exon Info From UCSC:
NM_001145031
NM_002658

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3890980Full LengthBC013575plasminogen activator, urokinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002649  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001145031 NP_001138503      
NM_002658 NP_002649 P00749 EC 3.4.21.73 Kringle
Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M15476 AAA61253 P00749 EC 3.4.21.73
K03226 AAC97138 P00749 EC 3.4.21.73
BC013575 AAH13575 P00749 EC 3.4.21.73
AY029537 AAK38734 Q96SE8  
BT007391 AAP36055 P00749 EC 3.4.21.73
AY820134 AAV70488 Q5PY49  
DQ893817 ABM84743    
D00244 BAA00175 P00749 EC 3.4.21.73
D11143 BAA01919 P00749 EC 3.4.21.73
AB208961 BAD92198 Q59GZ8  
AK312960 BAG35799 B2R7F2  
AK297940 BAG60256 B4DNJ4  
AK298560 BAG60754 P00749 EC 3.4.21.73
A18397 CAA01390    
A35395 CAA02215    
X02760 CAA26535 P00749 EC 3.4.21.73

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLAU NP_002649 R.norvegicus Plau 25619   NP_037217 71
M.musculus Plau 18792 Gene Info NP_032899 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta