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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GNAI2, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Sequence ID:NM_001166425
RefSeqGene ID:NG_016002
Entrez Gene ID:2771
Ensembl ID:ENSG00000114353

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 50273767 - 50295122

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2963802Full LengthBC014627guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
4403631Full LengthBC016995guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
4562585Full LengthBC012138guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002061  

Protein Infomation

NM_001166425 NP_001159897    
NM_002070 NP_002061 P04899 G-alpha

Related Sequences

J03004 AAA52556 P04899
BC012138 AAH12138 P04899
BC014627 AAH14627 Q96C71
BC016995 AAH16995 P04899
AF493906 AAM12620 P04899
AY677118 AAT78421 P04899
DQ892783 ABM83709  
DQ895908 ABM86834  
AK055574 BAG51536 B3KP24
AK096299 BAG53252 B3KTZ0
AK096595 BAG53334 B3KTZ0
AK126708 BAG54363 B3KX51
AK302330 BAG63662 P04899
AK304473 BAG65287 B4E2X5
X04828 CAA28512 P04899
CR456783 CAG33064 Q96C71

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GNAI2 NP_002061 R.norvegicus Gnai2 81664   NP_112297 99
M.musculus Gnai2 14678 Gene Info NP_032164 98
N.crassa NCU06493 3873271   XP_957133 55
S.cerevisiae GPA1 856394   NP_011868 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)