Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GPX1, glutathione peroxidase 1
Sequence ID:NM_000581
NM_201397
RefSeqGene ID:NG_012264
Entrez Gene ID:2876
Ensembl ID:ENSG00000233276

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 49394610 - 49395758

 Exon Info From UCSC:
NM_000581
NM_201397

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3505654Full LengthBC000742glutathione peroxidase 1
4301275Full LengthBC007865glutathione peroxidase 1
6452792Full LengthBC070258glutathione peroxidase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000572  NP_958799  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000581 NP_000572 P07203 EC 1.11.1.9 GSHPx
NM_201397 NP_958799     GSHPx

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M21304 AAA75389 P07203 EC 1.11.1.9
BC000742 AAH00742 P07203 EC 1.11.1.9
BC007865 AAH07865 Q7L4Q3  
BC070258 AAH70258 Q6NSD4  
X13709 CAA31992 P07203 EC 1.11.1.9
X13710 CAA31993 P07203 EC 1.11.1.9
Y00433 CAA68491 P07203 EC 1.11.1.9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GPX1 NP_000572 M.musculus Gpx1 14775 Gene Info NP_032186 88
R.norvegicus Gpx1 24404   NP_110453 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta