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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SRM, Spermidine synthase
Sequence ID:NM_003132
Entrez Gene ID:6723
Ensembl ID:ENSG00000116649

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36-p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 11114646 - 11120057

NM_003132 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12941111464811114941
2954171111501811115140
4185631111583711115982
5646471111606711116150
6488011111666011116813
8028941111885611118948
89510151111928111119401
101612731111983311120090

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820975Full LengthBC000309spermidine synthase
5420683Full LengthBC033106spermidine synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003123  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003132 NP_003123 P19623 EC 2.5.1.16 Spermine_synth

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M34338 AAA36633 P19623 EC 2.5.1.16
BC000309 AAH00309 P19623 EC 2.5.1.16
BC033106 AAH33106 P19623 EC 2.5.1.16
EU831556 ACE86475    
EU831469 ACE87156    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SRM NP_003123 M.musculus Srm 20810 Gene Info NP_033298 95
R.norvegicus Srm 84596   NP_445916 95
N.crassa NCU06727 3877045   XP_960907 60
C.elegans Y46G5A.19 174914   NP_001129829 58
S.cerevisiae SPE3 856182   NP_015394 58
A.gambiae AgaP_AGAP011126 1270799   XP_309520 58
S.pombe SPBC12C2.07c 2539919   NP_596015 57
D.melanogaster SpdS 41167   NP_731384 56
A.thaliana SPDS1 838993   NP_173794 53
A.thaliana SPDS2 843367   NP_177188 51
P.falciparum PF11_0301 810848   XP_001347972 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)