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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MBTPS1, membrane-bound transcription factor peptidase, site 1
Sequence ID:NM_003791
Entrez Gene ID:8720
Ensembl ID:ENSG00000140943

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 84087378 - 84095236

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40054074Full LengthBC114961membrane-bound transcription factor peptidase, site 1
40054075Full LengthBC114555membrane-bound transcription factor peptidase, site 1
4816102IncompleteBC026330membrane-bound transcription factor peptidase, site 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003782  

Protein Infomation

NM_003791 NP_003782 Q14703 EC Peptidase_S8

Related Sequences

BC114555 AAI14556 Q14703 EC
BC114961 AAI14962 Q14703 EC
D42053 BAA07653 Q14703 EC
AK291773 BAF84462 A8K6V8  
AK091212 BAG52308 A6NMF3  
AK299067 BAG61133 B4DR21  
AL133583 CAB63727 Q14703 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MBTPS1 NP_003782 R.norvegicus Mbtps1 89842   NP_446021 97
M.musculus Mbtps1 56453 Gene Info NP_001161382 96
A.gambiae AgaP_AGAP012203 1280482   XP_320328 65
D.melanogaster S1P 40399   NP_649337 56
A.thaliana S1P 832086   NP_197467 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta