Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PKD1, polycystic kidney disease 1 (autosomal dominant)
Sequence ID:NM_000296
NM_001009944
RefSeqGene ID:NG_008617
Entrez Gene ID:5310
Ensembl ID:ENSG00000008710

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
POLYCYSTIC KIDNEY DISEASE, ADULT TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 2140985 - 2159854

 Exon Info From UCSC:
NM_000296
NM_001009944

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000287  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000296 NP_000287   Lectin_C
LRR_1
PKD
LRRNT
LRRCT
PLAT
WSC
GPS
REJ
I-set
PKD_channel
NM_001009944 NP_001009944    

Related Sequences

 
mRNAGenPeptSwissProt
L33243 AAC37576 P98161
U24497 AAC50128 P98161
AB209025 BAD92262 Q59GT4
AB209675 BAD92912 Q59EY6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PKD1 NP_001009944 M.musculus Pkd1 18763 Gene Info NP_038658 79
R.norvegicus Pkd1 24650   XP_002727800 79

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)