Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SERPINC1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Sequence ID:NM_000488
RefSeqGene ID:NG_012462
Entrez Gene ID:462
Ensembl ID:ENSG00000117601

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
THROMBOPHILIA DUE TO ANTITHROMBIN III DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 173872946 - 174256782

NM_000488 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
2262173872942173873202
263327173876587173876651
328718173878689173879079
719856173879891173880028
8571072173880936173881151
10731439173883690173884056
14401599173886356173886515

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4734914Full LengthBC022309serpin peptidase inhibitor, clade C (antithrombin), member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000479  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000488 NP_000479 P01008 Serpin

Related Sequences

 
mRNAGenPeptSwissProt
AF130100 AAG35525 P01008
BC022309 AAH22309 Q8TCE1
D29832 BAA06212 P01008
AK312654 BAG35537 P01008

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SERPINC1 NP_000479 M.musculus Serpinc1 11905 Gene Info NP_543120 88
R.norvegicus Serpinc1 304917   NP_001012027 86
A.thaliana AT1G64010 842704   NP_176584 34
A.thaliana SRP3 842706   NP_176586 34
A.thaliana AT1G62160 3767608   NP_176407 33
A.thaliana AT1G62170 842513   NP_176408 30
A.thaliana SRP2 815941   NP_179060 30
A.thaliana AT2G35580 818123   NP_181101 30

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta