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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ADSL, adenylosuccinate lyase
Sequence ID:NM_000026
RefSeqGene ID:NG_007993
Entrez Gene ID:158
Ensembl ID:ENSG00000239900

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, parathyroid, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 40742506 - 40762750

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3352079Full LengthBC000253adenylosuccinate lyase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000017  

Protein Infomation

NM_000026 NP_000017 P30566 EC Lyase_1
NM_001123378 NP_001116850      

Related Sequences

AF067853 AAC21560 P30566 EC
AF067854 AAC21561 P30566 EC
S60710 AAC60603 P30566 EC
BC000253 AAH00253 P30566 EC
DQ893326 ABM84252    
DQ896642 ABM87641    
AK291091 BAF83780 A8K4X6  
AK298187 BAG60458 B4DP46  
AK300705 BAG62384 B4DUM2  
X65867 CAA46696 P30566 EC
X65867 CAA46697 P30566 EC
CR456368 CAG30254 P30566 EC
CU012935 CAK54366    
CU013223 CAK54665    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ADSL NP_000017 M.musculus Adsl 11564 Gene Info NP_033764 94
R.norvegicus Adsl 315150   NP_001123975 93
D.melanogaster CG3590 42051   NP_650586 68
A.gambiae AgaP_AGAP002378 1273584   XP_312577 67
S.cerevisiae ADE13 851073   NP_013463 65
S.pombe ade8 2539985   NP_596735 63
N.crassa NCU06187 3879147   XP_962999 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)