Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ALPL, alkaline phosphatase, liver/bone/kidney
Sequence ID:NM_000478
NM_001127501
NM_001177520
RefSeqGene ID:NG_008940
Entrez Gene ID:249
Ensembl ID:ENSG00000162551

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPOPHOSPHATASIA, ADULT 
HYPOPHOSPHATASIA, CHILDHOOD 
HYPOPHOSPHATASIA, INFANTILE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 21835938 - 21904902

 Exon Info From UCSC:
NM_000478
NM_001127501
NM_001177520

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5087597Full LengthBC021289alkaline phosphatase, liver/bone/kidney
5752191Full LengthBC110909alkaline phosphatase, liver/bone/kidney
5754297Full LengthBC066116alkaline phosphatase, liver/bone/kidney
6181160Full LengthBC090861alkaline phosphatase, liver/bone/kidney
8991881Full LengthBC126165alkaline phosphatase, liver/bone/kidney
9020312Full LengthBC136325alkaline phosphatase, liver/bone/kidney

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000469  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000478 NP_000469 P05186 EC 3.1.3.1 Alk_phosphatase
NM_001127501 NP_001120973      
NM_001177520 NP_001170991      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC021289 AAH21289 P05186 EC 3.1.3.1
BC066116 AAH66116 P05186 EC 3.1.3.1
BC090861 AAH90861 P05186 EC 3.1.3.1
BC110909 AAI10910 P05186 EC 3.1.3.1
BC126165 AAI26166 P05186 EC 3.1.3.1
BC136325 AAI36326 P05186 EC 3.1.3.1
HQ258287 ADR83041    
AB011406 BAA32129 P05186 EC 3.1.3.1
AB012643 BAA88367 Q9UIL5  
AB209814 BAD93051 P05186 EC 3.1.3.1
AK312667 BAG35549 B2R6Q2  
AK293184 BAH11467 B7Z1D1  
AK295608 BAH12123 P05186 EC 3.1.3.1
AK298085 BAH12722 P05186 EC 3.1.3.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ALPL NP_000469 R.norvegicus Alpl 25586   NP_037191 90
M.musculus Alpl 11647 Gene Info NP_031457 90
A.gambiae AgaP_AGAP007300 1269868   XP_308522 47
D.melanogaster CG5656 40372   NP_649315 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta