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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PFKM, phosphofructokinase, muscle
Sequence ID:NM_000289
NM_001166686
NM_001166687
NM_001166688
RefSeqGene ID:NG_016199
Entrez Gene ID:5213
Ensembl ID:ENSG00000152556

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GLYCOGEN STORAGE DISEASE VII 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 48499888 - 48539887

 Exon Info From UCSC:
NM_000289
NM_001166686
NM_001166687
NM_001166688

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964710Full LengthBC000534phosphofructokinase, muscle
2964710Full LengthBC012799phosphofructokinase, muscle
2964710Full LengthBC013298phosphofructokinase, muscle
4100117Full LengthBC021203phosphofructokinase, muscle
4124137IncompleteBC007798phosphofructokinase, muscle

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000280  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000289 NP_000280 P08237 EC 2.7.1.11 PFK
NM_001166686 NP_001160158      
NM_001166687 NP_001160159      
NM_001166688 NP_001160160      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M26066 AAA60068 P08237 EC 2.7.1.11
J05533 AAA79220 P08237 EC 2.7.1.11
U24183 AAA91985 Q7KYX9  
BC000534 AAH00534 P08237 EC 2.7.1.11
BC007798 AAH07798 Q96I60  
BC012799 AAH12799 P08237 EC 2.7.1.11
BC013298 AAH13298 P08237 EC 2.7.1.11
BC021203 AAH21203 P08237 EC 2.7.1.11
AK126229 BAC86498 Q6ZTT1  
AK303681 BAG64674 B4E162  
Y00698 CAA68692 P08237 EC 2.7.1.11
BX537703 CAD97816 Q7Z683  
CR541698 CAG46499 Q7KYX9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PFKM NP_001160158 M.musculus Pfkm 18642 Gene Info NP_067489 98
R.norvegicus Pfkm 65152   NP_113903 97
A.gambiae AgaP_AGAP007642 1269584   XP_564589 63
D.melanogaster Pfk 36060   NP_724891 61
C.elegans phosphofructokinase 180583   NP_741738 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta