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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LEF1, Lymphoid enhancer-binding factor 1
Sequence ID:NM_016269
NM_001130713
NM_001130714
NM_001166119
RefSeqGene ID:NG_015798
Entrez Gene ID:51176
Ensembl ID:ENSG00000138795

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q23-q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 108991813 - 109000750

 Exon Info From UCSC:
NM_016269
NM_001130713
NM_001130714
NM_001166119

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5269696Full LengthBC040559lymphoid enhancer-binding factor 1
6054813Full LengthBC050632lymphoid enhancer-binding factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057353  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001130713 NP_001124185    
NM_001130714 NP_001124186    
NM_001166119 NP_001159591    
NM_016269 NP_057353 Q9UJU2 HMG_box
CTNNB1_binding

Related Sequences

 
mRNAGenPeptSwissProt
AF198532 AAF13268 Q9UJU2
AF288571 AAG01022 Q9UJU2
AF294627 AAG26886 Q9UJU2
BC040559 AAH40559 Q9UJU2
BC050632 AAH50632 Q9UJU2
EU446873 ABZ92402  
AK294395 BAG57649 Q9UJU2
AK303143 BAG64247 B4DZY5
AK303272 BAH13928 B7Z8E2
AL049409 CAH56421 Q659G9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LEF1 NP_057353 M.musculus Lef1 16842 Gene Info NP_034833 98
R.norvegicus Lef1 161452   NP_569113 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta