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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SUCLA2, Succinate-CoA ligase, ADP-forming, beta subunit
Sequence ID:NM_003850
RefSeqGene ID:NG_008241
Entrez Gene ID:8803
Ensembl ID:ENSG00000136143

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MITOCHONDRIAL DNA DEPLETION SYNDROME 2 (MYOPATHIC TYPE)TK2

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q12.2-q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 48516790 - 48575462

 Exon Info From UCSC:
NM_003850

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4829291Full LengthBC027587succinate-CoA ligase, ADP-forming, beta subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003841  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003850 NP_003841 Q9P2R7 EC 6.2.1.5 Ligase_CoA
ATP-grasp_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF058953 AAC64396 Q9P2R7 EC 6.2.1.5
BC027587 AAH27587 Q9P2R7 EC 6.2.1.5
AF087890 AAP97189 Q7Z503  
AK001458 BAA91703 Q9P2R7 EC 6.2.1.5
AK001847 BAA91939 Q9P2R7 EC 6.2.1.5
AB035863 BAA92873 Q9P2R7 EC 6.2.1.5
AK315513 BAG37894 Q9P2R7 EC 6.2.1.5
AK299437 BAG61414 B4DRV2  
AK302311 BAG63649 B4DY87  
AK316041 BAH14412 B7Z9S6  
AK316271 BAH14642 B7ZAF6  
AL080096 CAB45708 Q9Y4T0  
BX640602 CAE45708 Q6N0B1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SUCLA2 NP_003841 M.musculus Sucla2 20916 Gene Info NP_035636 91
R.norvegicus Sucla2 361071   NP_001101857 89
C.elegans F47B10.1 181280   NP_509821 63
A.gambiae AgaP_AGAP004744 1278481   XP_318074 62
D.melanogaster skap 41067   NP_001097713 60
N.crassa NCU08471 3879462   XP_963313 59
S.pombe SPCC1620.08 2539168   NP_588466 55
A.thaliana AT2G20420 816561   NP_179632 54
S.cerevisiae LSC2 853159   NP_011760 47
P.falciparum PF14_0295 811877   XP_001348469 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)