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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. WNK1, WNK lysine deficient protein kinase 1
Sequence ID:NM_001184985
NM_014823
NM_018979
NM_213655
RefSeqGene ID:NG_007984
Entrez Gene ID:65125
Ensembl ID:ENSG00000060237

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
NEUROPATHY,HEREDITARY SENSORY AND AUTONOMIC, TYPE II 
PSEUDOHYPOALDOSTERONISM, TYPE IIC 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 862933 - 1018567

 Exon Info From UCSC:
NM_001184985
NM_014823
NM_018979
NM_213655

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069138Full LengthBC172444WNK lysine deficient protein kinase 1
3445410IncompleteBC013629WNK lysine deficient protein kinase 1
40126884IncompleteBC141881WNK lysine deficient protein kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_061852  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001184985 NP_001171914      
NM_014823 NP_055638      
NM_018979 NP_061852 Q9H4A3 EC 2.7.11.1 Pkinase
NM_213655 NP_998820      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF061944 AAF31483 Q9H4A3 EC 2.7.11.1
BC013629 AAH13629 Q96CZ6  
BC130467 AAI30468 Q9H4A3 EC 2.7.11.1
BC130469 AAI30470 Q9H4A3 EC 2.7.11.1
BC141881 AAI41882 A5D8Z4  
BC172444 AAI72444    
AY231477 AAO46160 Q9H4A3 EC 2.7.11.1
JQ358908 AEY99342 H6WZW3  
AB002342 BAA20802 Q9H4A3 EC 2.7.11.1
AJ296290 CAC15059 Q9H4A3 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens WNK1 NP_061852 M.musculus Wnk1 232341 Gene Info NP_941992 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)