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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. CS, citrate synthase
Sequence ID:NM_004077
Entrez Gene ID:1431
Ensembl ID:ENSG00000062485

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 56666867 - 56693985

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542491Full LengthBC010106citrate synthase
6484456Full LengthBC072016citrate synthase
3509003IncompleteBC000105citrate synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004068  

Protein Infomation

NM_004077 NP_004068 O75390 EC Citrate_synt

Related Sequences

AF047042 AAC25560 O75390 EC
BC000105 AAH00105 O75390 EC
BC010106 AAH10106 O75390 EC
BC072016 AAH72016 O75390 EC
BT007414 AAP36082 O75390 EC
AF053631 AAQ13428 O75390 EC
DQ403132 ABD77265 Q0QEL2  
AK074956 BAC11314 O75390 EC
AK095856 BAG53146 B3KTN4  
AK296249 BAG58964 B4DJV2  
AK293263 BAH11477 B7Z1E1  
BX640838 CAE45911 O75390 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CS NP_004068 R.norvegicus Cs 170587   NP_570111 95
M.musculus Cs 12974 Gene Info NP_080720 94
A.gambiae AgaP_AGAP012048 1280620   XP_320478 75
D.melanogaster kdn 31579   NP_572319 73
C.elegans cts-1 176437   NP_499264 69
A.thaliana ATCS 819042   NP_850415 63
S.cerevisiae CIT2 850361   NP_009931 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta