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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. STAT1, signal transducer and activator of transcription 1, 91kDa
Sequence ID:NM_007315
NM_139266
RefSeqGene ID:NG_008294
Entrez Gene ID:6772
Ensembl ID:ENSG00000115415

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
BCG INFECTION, GENERALIZED FAMILIALIFNGR1
IFNGR2
IL12B
IL12RB1

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q32.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 191840367 - 191878910

 Exon Info From UCSC:
NM_007315
NM_139266

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3627218Full LengthBC002704signal transducer and activator of transcription 1, 91kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009330  NP_644671  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_007315 NP_009330 P42224 SH2
STAT_alpha
STAT_bind
STAT_int
NM_139266 NP_644671   SH2
STAT_alpha
STAT_bind
STAT_int

Related Sequences

 
mRNAGenPeptSwissProt
M97935 AAB64012 P42224
BC002704 AAH02704 P42224
BC141921 AAI41922 A5D905
BT007241 AAP35905 P42224
EU832073 ACE86735  
EU831980 ACE87421  
GU211347 ADA59516 P42224
GU211348 ADA59517 D2KFR9
AK292604 BAF85293 P42224
AK315002 BAG37497 P42224
CR749636 CAH18430 P42224

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens STAT1 NP_009330 M.musculus Stat1 20846 Gene Info NP_033309 94
R.norvegicus Stat1 25124   NP_116001 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta