Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. LGMN, legumain
Sequence ID:NM_001008530
Entrez Gene ID:5641
Ensembl ID:ENSG00000100600

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 93170278 - 93214938

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3504506Full LengthBC003061legumain

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001008530  NP_005597  

Protein Infomation

NM_001008530 NP_001008530 Q53XC6
EC Peptidase_C13
NM_005606 NP_005597 Q53XC6
EC Peptidase_C13

Related Sequences

BC003061 AAH03061 Q99538 EC
BC013678 AAH13678 Q96CY7  
DQ891884 ABM82810    
DQ895070 ABM85996    
DQ895071 ABM85997    
EU176651 ABW03452    
D55696 BAA09530 Q99538 EC
AK291534 BAF84223 A8K669  
AK291560 BAF84249 Q53XC6  
AK297074 BAH12490 B7Z4A4  
AK297780 BAH12664 B7Z4S8  
Y09862 CAA70989 Q53XC6
BX161380 CAD61872 Q86TV3  
BX161422 CAD61895 Q86TV2  
BX161434 CAD61906 Q53XC6
CR457406 CAG33687 Q6I9U9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens LGMN NP_005597 R.norvegicus Lgmn 63865   NP_071562 83
M.musculus Lgmn 19141 Gene Info NP_035305 83
C.elegans T28H10.3 179714   NP_506137 43
A.thaliana DELTA-VPE 821565   NP_188656 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)