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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HERC2, HECT and RLD domain containing E3 ubiquitin protein ligase 2
Sequence ID:NM_004667
RefSeqGene ID:NG_016355
Entrez Gene ID:8924
Ensembl ID:ENSG00000128731

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 28565277 - 28567265

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5262032IncompleteBC045544hect domain and RLD 2
9094352IncompleteBC172191hect domain and RLD 2
9094487IncompleteBC172911hect domain and RLD 2
40121629IncompleteBC148318hect domain and RLD 2

Protein Infomation

NM_004667 NP_004658 O95714  

Related Sequences

AF071172 AAD08657 O95714
BC148318 AAI48319 A8KAQ8
AL834183 CAD38880 Q8ND39

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HERC2 NP_004658 M.musculus Herc2 15204 Gene Info NP_034548 96
R.norvegicus Herc2 308669   NP_001100990 96
A.gambiae AgaP_AGAP011823 1280824   XP_552411 49
D.melanogaster HERC2 33035   NP_608388 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)