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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. KDSR, 3-ketodihydrosphingosine reductase
Sequence ID:NM_002035
RefSeqGene ID:NG_028249
Entrez Gene ID:2531
Ensembl ID:ENSG00000119537

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, parathyroid, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:18q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 60994970 - 60995552

NM_002035 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3636291Full LengthBC0087973-ketodihydrosphingosine reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002026  

Protein Infomation

NM_002035 NP_002026 Q06136 EC adh_short

Related Sequences

BC008797 AAH08797 Q06136 EC
BT006782 AAP35428 Q06136 EC
AK312360 BAG35278 Q06136 EC
AK297670 BAG60032 B4DMX0  
X63657 CAA45197 Q06136 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens KDSR NP_002026 M.musculus Kdsr 70750 Gene Info NP_081810 93
R.norvegicus Kdsr 360833   NP_001101812 93
A.gambiae AgaP_AGAP003984 1278801   XP_318434 42
A.thaliana AT3G06060 819779   NP_187257 38
D.melanogaster CG10425 43043   NP_651363 38
A.thaliana AT5G19200 832040   NP_197421 36
S.pombe SPCC1450.15 2539289   NP_588314 35
N.crassa NCU00302 3873943   XP_957773 30
S.cerevisiae TSC10 852568   NP_009824 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)