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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FAH, fumarylacetoacetate hydrolase (fumarylacetoacetase)
Sequence ID:NM_000137
RefSeqGene ID:NG_012833
Entrez Gene ID:2184
Ensembl ID:ENSG00000103876

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
TYROSINEMIA, TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 80445238 - 80478551

 Exon Info From UCSC:
NM_000137

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3139988Full LengthBC002527fumarylacetoacetate hydrolase (fumarylacetoacetase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000128  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000137 NP_000128 P16930 EC 3.7.1.2 FAA_hydrolase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M55150 AAA52422 P16930 EC 3.7.1.2
BC002527 AAH02527 P16930 EC 3.7.1.2
BT007160 AAP35824 P16930 EC 3.7.1.2
D28440 BAA05806    
AK313951 BAG36668 P16930 EC 3.7.1.2
AK297965 BAH12698 B7Z4W2  
X51728 CAA36016 P16930
Q53XA7
EC 3.7.1.2
BX537608 CAD97795 Q53XA7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FAH NP_000128 M.musculus Fah 14085 Gene Info NP_034306 89
R.norvegicus Fah 29383   NP_058877 89
C.elegans fumarylacetoacetase 180918   NP_509083 65
A.gambiae AgaP_AGAP005865 1276533   XP_315893 63
D.melanogaster Faa 45577   NP_524830 62
A.thaliana AT1G12050 837757   NP_172669 59
N.crassa NCU05537 3876646   XP_960499 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)