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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. VEGFA, vascular endothelial growth factor A
Sequence ID:NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
RefSeqGene ID:NG_008732
Entrez Gene ID:7422
Ensembl ID:ENSG00000112715

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
WFS1
WFS1
MICROVASCULAR COMPLICATIONS OF DIABETES 1ACE

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 43738983 - 43752299

 Exon Info From UCSC:
NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069001Full LengthBC172307vascular endothelial growth factor A
4150451IncompleteBC011177vascular endothelial growth factor A
6006890IncompleteBC065522vascular endothelial growth factor A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001020537  NP_001020541  NP_003367  NP_001020540  NP_001020538  NP_001020539  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001025366 NP_001020537   PDGF
NM_001025367 NP_001020538   PDGF
NM_001025368 NP_001020539   PDGF
NM_001025369 NP_001020540   PDGF
NM_001025370 NP_001020541   PDGF
NM_001033756 NP_001028928    
NM_001171622 NP_001165093    
NM_001171623 NP_001165094 P15692  
NM_001171624 NP_001165095    
NM_001171625 NP_001165096    
NM_001171626 NP_001165097    
NM_001171627 NP_001165098    
NM_001171628 NP_001165099    
NM_001171629 NP_001165100    
NM_001171630 NP_001165101    
NM_001204384 NP_001191313    
NM_001204385 NP_001191314    
NM_003376 NP_003367   PDGF

Related Sequences

 
mRNAGenPeptSwissProt
M32977 AAA35789 P15692
M27281 AAA36807 P15692
AF062645 AAC16730 P15692
S85192 AAC63102 P15692
AF022375 AAC63143 P15692
AF091352 AAD55345 P15692
AF214570 AAF19659 P15692
BC011177 AAH11177 Q96FD9
BC065522 AAH65522 P15692
BC172307 AAI72307  
AY047581 AAK95847 P15692
AF430806 AAL27435 P15692
AF486837 AAM03108 P15692
AY263145 AAP86646 Q6WZM0
AF323587 AAQ14857 Q71S09
AY766116 AAV34601 P15692
DQ229900 ABB58912 P15692
EU832814 ACE87825  
GQ129408 ACT64542  
AB021221 BAA78418 P15692
AB209485 BAD92722 Q59FH5
AB451322 BAG70136 P15692
AB451451 BAG70265 P15692
AJ010438 CAA09179 P15692
X62568 CAA44447 P15692

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens VEGFA NP_003367 R.norvegicus Vegfa 83785   NP_114024 85
M.musculus Vegfa 22339 Gene Info NP_001020421 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta