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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AKR1C2, aldo-keto reductase family 1, member C2
Sequence ID:NM_001135241
NM_001354
NM_205845
RefSeqGene ID:NG_031852
Entrez Gene ID:1646
Ensembl ID:ENSG00000151632

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10p15-p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 5048990 - 5052494

 Exon Info From UCSC:
NM_001135241
NM_001354
NM_205845

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3681970Full LengthBC007024aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
3877666Full LengthBC063574aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135241 NP_001128713      
NM_001354 NP_001345 P52895 EC 1.1.1.213
EC 1.3.1.20
Aldo_ket_red
NM_205845 NP_995317 P52895 EC 1.1.1.213
EC 1.3.1.20
Aldo_ket_red

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U05598 AAA20937 P52895 EC 1.1.1.213
EC 1.3.1.20
S68330 AAD14013 P52895 EC 1.1.1.213
EC 1.3.1.20
BC007024 AAH07024 P52895 EC 1.1.1.213
EC 1.3.1.20
BC063574 AAH63574 P52895 EC 1.1.1.213
EC 1.3.1.20
BT006653 AAP35299 P52895 EC 1.1.1.213
EC 1.3.1.20
DQ890680 ABM81606    
DQ893862 ABM84788    
AB021654 BAA36169 P52895 EC 1.1.1.213
EC 1.3.1.20
AB031084 BAA92884 P52895 EC 1.1.1.213
EC 1.3.1.20
AB209017 BAD92254 Q59GU2  
AK290304 BAF82993 P52895 EC 1.1.1.213
EC 1.3.1.20
AK296419 BAG59081 B4DK69  
AK296686 BAG59281 P52895 EC 1.1.1.213
EC 1.3.1.20

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKR1C2 NP_001345 H.sapiens AKR1C1 1645 Gene Info NP_001344 98
M.musculus Akr1c21 77337 Gene Info NP_084177 73
R.norvegicus Akr1c2 291283   NP_001013075 71
A.thaliana AT1G59950 842289   NP_176203 44
A.thaliana AT1G59960 842290   NP_176204 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)