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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. XRCC3, X-ray repair complementing defective repair in Chinese hamster cells 3
Sequence ID:NM_001100119
NM_005432
NM_001100118
RefSeqGene ID:NG_011516
Entrez Gene ID:7517
Ensembl ID:ENSG00000126215

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BREAST CANCERAKT1
ATM
BARD1
BRCA1
BRCA2
BRIP1
CASP8
CDH1
CHEK2
CHEK2
HMMR
KRAS
NQO2
NQO2
PALB2
PHB
PIK3CA
PIK3CA
PPM1D
RAD51
RAD54L
RB1CC1
SLC22A18
TP53
TP53
TSG101

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 104163953 - 104179259

 Exon Info From UCSC:
NM_001100119
NM_005432
NM_001100118

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3139703Full LengthBC001036X-ray repair complementing defective repair in Chinese hamster cells 3
4138588Full LengthBC011725X-ray repair complementing defective repair in Chinese hamster cells 3
3543559IncompleteBC002949X-ray repair complementing defective repair in Chinese hamster cells 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005423  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001100118 NP_001093588    
NM_001100119 NP_001093589    
NM_005432 NP_005423 O43542
Q53XC8
Rad51

Related Sequences

 
mRNAGenPeptSwissProt
AF035586 AAC05368 O43542
Q53XC8
BC001036 AAH01036 O43542
Q53XC8
BC002949 AAH02949 O43542
BC011725 AAH11725 O43542
BT007417 AAP36085 O43542
Q53XC8
DQ892162 ABM83088  
DQ895355 ABM86281  
AK022829 BAG51121 Q53XC8
AK023646 BAG51212 Q53XC8
AK124498 BAG54042 Q53XC8
BX161398 CAD61884 O43542
Q53XC8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens XRCC3 NP_001093588 R.norvegicus LOC100359601 100359601   XP_002729772 75
M.musculus Xrcc3 74335 Gene Info NP_083151 74
D.melanogaster spn-B 41746   NP_476740 40
N.crassa NCU01771 3873300   XP_957194 38
A.thaliana XRCC3 835850   NP_200554 36
S.pombe rhp57 2542007   NP_593627 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)