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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DNASE1, deoxyribonuclease I
Sequence ID:NM_005223
RefSeqGene ID:NG_009285
Entrez Gene ID:1773
Ensembl ID:ENSG00000213918

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
?SYSTEMIC LUPUS ERYTHEMATOSUS, OR PROTECTION AGAINSTBANK1
C4A
C4A
FASLG
FCGR2B
FCGR3A
ITGAX
PDCD1
PTPN22
STAT4
STAT4
TREX1
TREX1
TREX1

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 3713969 - 3715458

NM_005223 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1210637029393705044
2107225437053733705520
2255234337058493705937
2344242737061023706185
2428254337066383706753
2544265637069993707111
2657281137071873707341
2812290837077203707816
2909309737079063708094

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4594247Full LengthBC029437deoxyribonuclease I
4851821IncompleteBC015002deoxyribonuclease I

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_005223 NP_005214 P24855 EC 3.1.21.1 Exo_endo_phos

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M55983 AAA63170 P24855 EC 3.1.21.1
BC029437 AAH29437 P24855 EC 3.1.21.1
DQ892098 ABM83024    
DQ895291 ABM86217    
AB188151 BAE96964 P24855 EC 3.1.21.1
AB188152 BAE96965 P24855 EC 3.1.21.1
AK300914 BAG62547 B4DV35  
AJ298844 CAC12813 P24855 EC 3.1.21.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DNASE1 NP_005214 M.musculus Dnase1 13419 Gene Info NP_034191 79
R.norvegicus Dnase1 25633   NP_037229 78

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)