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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOS1, Son of sevenless homolog 1 (Drosophila)
Sequence ID:AL833457
RefSeqGene ID:NG_007530
Entrez Gene ID:6654
Ensembl ID:ENSG00000115904

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
FIBROMATOSIS, GINGIVAL 
NOONAN SYNDROME 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 39247088 - 39279028


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100014292BC140215son of sevenless homolog 1 (Drosophila)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005633 NP_005624 Q07889 Histone
PH
RasGEF
RasGEF_N
RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
L13857 AAA35913 Q07889
BC140215 AAI40216  
AB209140 BAD92377 Q59GG9
AK290228 BAF82917 Q07889
AK301960 BAG63374 B4DXG2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOS1 NP_005624 M.musculus Sos1 20662 Gene Info NP_033257 98
R.norvegicus Sos1 313845   NP_001094186 98
A.gambiae AgaP_AGAP009180 1280136   XP_319944 49
D.melanogaster Sos 34790   NP_476597 48
C.elegans sos-1 178846   NP_504235 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta