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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KRT4, keratin 4
Sequence ID:NM_002272
RefSeqGene ID:NG_007380
Entrez Gene ID:3851
Ensembl ID:ENSG00000170477

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    cervix, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, lung, mammary gland, ovary, pancreas, placenta, pooled tissue, prostate, stem cell, thyroid, uncharacterized tissue
  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
WHITE SPONGE NEVUSKRT13

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:Unknown

NM_002272 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
27025320033353201033
7037375320114253201176
7389585320142753201647
95910845320207753202202
108512495320246953202633
125013455320316653203261
134614065320453953204599
140716215320554653205760
162225765320738053208334

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5453644Full LengthBC042174keratin 4
2989740IncompleteBC003630keratin 4
3927526IncompleteBC032132keratin 4

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002272 NP_002263 P19013 Filament

Related Sequences

 
mRNAGenPeptSwissProt
BC003630 AAH03630 P19013
BC032132 AAH32132 Q6PIN2
BC042174 AAH42174 P19013
EU832441 ACE86926  
EU832356 ACE87613  
AK296582 BAG59202 B4DKJ0
AK299394 BAG61379 B4DRR7
AK299400 BAG61384 B4DRS2
AK299451 BAG61423 B4DRW1
X07695 CAA30534 P19013
X67683 CAA47914 P19013

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KRT4 NP_002263 M.musculus Krt4 16682 Gene Info NP_032501 83
R.norvegicus Krt4 315323   NP_001008806 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)