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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. RAPGEF2, Rap guanine nucleotide exchange factor (GEF) 2
Sequence ID:NM_014247
Entrez Gene ID:9693
Ensembl ID:ENSG00000109756

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q32.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 160189245 - 160281299

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125872Full LengthBC117321Rap guanine nucleotide exchange factor (GEF) 2

Protein Infomation

NM_014247 NP_055062 Q9Y4G8  

Related Sequences

BC117321 AAI17322 Q17RH5
AB002311 BAA20772 Q9Y4G8
AK294459 BAG57693 B4DG82
AL117397 CAB55899 Q9UFT5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens RAPGEF2 NP_055062 M.musculus Rapgef2 76089 Gene Info NP_001093094 95
R.norvegicus Rapgef2 310533   NP_001101154 94
D.melanogaster Gef26 33881   NP_001137797 51
A.gambiae AgaP_AGAP009261 1280224   XP_553211 49
C.elegans pxf-1 177894   NP_001023389 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta