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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MECP2, methyl CpG binding protein 2 (Rett syndrome)
Sequence ID:NM_001110792
NM_004992
RefSeqGene ID:NG_007107
Entrez Gene ID:4204
Ensembl ID:ENSG00000169057

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, adrenal medulla, b-cell, bone, brain, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, testis, thymus, uncharacterized tissue, uterus, vascular
  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ANGELMAN SYNDROMECDKL5
UBE3A
AUTISM SUSCEPTIBILITY, X-LINKED3 
ENCEPHALOPATHY, NEONATAL SEVERE 
MENTAL RETARDATION, X-LINKED SYNDROMIC, LUBS TYPE 
MENTAL RETARDATION, X-LINKED, SYNDROMIC13 
RETT SYNDROMECDKL5

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 153297823 - 153402578

 Exon Info From UCSC:
NM_001110792
NM_004992

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3956518Full LengthBC011612methyl CpG binding protein 2 (Rett syndrome)
4476493IncompleteBC031833methyl CpG binding protein 2 (Rett syndrome)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001110792 NP_001104262    
NM_004992 NP_004983 P51608 MBD

Related Sequences

 
mRNAGenPeptSwissProt
L37298 AAC32737 P51608
AF158180 AAF33023 P51608
BC011612 AAH11612 P51608
BC031833 AAH31833 Q8N5Q5
AY541280 AAS55455 P51608
DQ891939 ABM82865  
EU176656 ABW03457  
GQ203293 ACS92725 C6KG44
GQ203294 ACS92726 C6KG45
GQ896382 ACY24448 D0UU70
GU479943 ADD17354 D3YJ43
GU812285 ADE87881 D5L9I4
GU812286 ADE87882 D5L9I5
HM020402 ADG26557 D6QZ43
HM156732 ADK25710 D9ZNA4
HM156733 ADK25711 D3YJ43
HQ154629 ADM88591 E1B2J3
HQ141377 ADW01219 E9LUH3
HQ141378 ADW01220 E9LUH4
AB209464 BAD92701 Q59FJ6
AK289444 BAF82133 A8K079
X89430 CAA61599 P51608
X99686 CAA68001 P51608
Y12643 CAA73190 P51608
AJ132917 CAB46446 P51608
BX538060 CAD97991 P51608
AM392557 CAL37435  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MECP2 NP_001104262 M.musculus Mecp2 17257 Gene Info NP_001075448 96
R.norvegicus Mecp2 29386   NP_073164 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)