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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HTRA2, HtrA serine peptidase 2
Sequence ID:NM_013247
NM_145074
RefSeqGene ID:NG_012163
Entrez Gene ID:27429
Ensembl ID:ENSG00000115317

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PARKINSON DISEASE 13 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 74757116 - 74760302

 Exon Info From UCSC:
NM_013247
NM_145074

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3508944Full LengthBC000096HtrA serine peptidase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_659540  NP_037379  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_013247 NP_037379 O43464 EC 3.4.21.108 Trypsin
PDZ
NM_145074 NP_659540     Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF020760 AAB94569 O43464 EC 3.4.21.108
AF141305 AAF66596 O43464 EC 3.4.21.108
AF141306 AAF66597 O43464 EC 3.4.21.108
AF141307 AAF66598 O43464 EC 3.4.21.108
AF184911 AAG13126 O43464 EC 3.4.21.108
BC000096 AAH00096 O43464 EC 3.4.21.108
DQ891822 ABM82748    
DQ895009 ABM85935    
EU176308 ABW03759    
AK291977 BAF84666 A8K7G2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HTRA2 NP_037379 R.norvegicus Htra2 297376   NP_001100069 87
M.musculus Htra2 64704 Gene Info NP_062726 85
A.gambiae AgaP_AGAP000240 1272021   XP_310886 58
D.melanogaster HtrA2 41756   NP_650366 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)