Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP3A4, cytochrome P450, family 3, subfamily A, polypeptide 4
Sequence ID:NM_001202855
NM_017460
NM_001202856
NM_001202857
RefSeqGene ID:NG_008421
Entrez Gene ID:1576
Ensembl ID:ENSG00000160868

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 99355572 - 99381713


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262313Full LengthBC069418cytochrome P450, family 3, subfamily A, polypeptide 4
8069137Full LengthBC101631cytochrome P450, family 3, subfamily A, polypeptide 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_059488  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001202855 NP_001189784      
NM_017460 NP_059488 Q6GRK0
P08684
EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
p450
NM_022820 NP_073731     p450
NM_057095 NP_476436 Q75MK3
Q9HB55
EC 1.14.14.1 p450
NM_057096 NP_476437     p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M13785 AAA35742 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
M14096 AAA35744 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
M18907 AAA35745 Q6GRK0
P08684
EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
J04449 AAA35747 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
AF182273 AAF13598 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
AF280108 AAG33009 Q75MK3
Q9HB55
EC 1.14.14.1
AF280109 AAG33010 Q9HB55 EC 1.14.14.1
AF280110 AAG33011 Q9HB55 EC 1.14.14.1
AF280111 AAG33012 Q9HB55 EC 1.14.14.1
AF280112 AAG33013 Q9HB51  
AF280113 AAG33014 Q9HB50  
BC069418 AAH69418 Q6GRK0  
BC100981 AAI00982 Q495Y1  
BC100982 AAI00983 Q495Y0  
BC101631 AAI01632 Q6GRK0  
AF319634 AAK00325 Q75MK3
Q9HB55
EC 1.14.14.1
AF337813 AAK38841 Q75MK3
Q9HB55
EC 1.14.14.1
AY390423 AAQ92351 Q9HB55 EC 1.14.14.1
AY390424 AAQ92352 Q9HB55 EC 1.14.14.1
AY390425 AAQ92353 Q75MK3
Q9HB55
EC 1.14.14.1
AY390426 AAQ92354 Q9HB55 EC 1.14.14.1
DQ924960 ABI96208 Q6GRK0  
D00003 BAA00001 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
AK312967 BAG35806 Q6GRK0  
AK298451 BAG60667 B4DPQ5  
AK298462 BAG60675 B4DPR3  
X12387 CAA30944 P08684 EC 1.14.13.32
EC 1.14.13.157
EC 1.14.13.97
EC 1.14.13.67
AJ563375 CAD91343 Q86SK3  
AJ563377 CAD91345 Q86SK2  
AJ563376 CAD91644 Q7Z2G5  
AJ563376 CAD91645 Q7Z448  
AJ563378 CAD91646 Q7Z2G5  
AJ563379 CAD91648 Q7Z2G5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP3A4 NP_059488 R.norvegicus Cyp3a2 266682   NP_695224 72
A.gambiae AgaP_AGAP012293 5667962   XP_001689238 41
A.gambiae AgaP_AGAP012296 3291548   XP_551896 37
A.gambiae CYP9L1 1280396   XP_320243 37
A.gambiae AgaP_AGAP012292 4577527   XP_001238280 37
A.gambiae AgaP_AGAP012294 4577529   XP_001238278 36
A.gambiae AgaP_AGAP012850 1267986   XP_561320 35
C.elegans cyp-25A3 4363046   NP_001040850 33
C.elegans cyp-25A1 183247   NP_497775 32
C.elegans cyp-25A2 175495   NP_497776 32
C.elegans cyp-25A4 183248   NP_497779 32
C.elegans cyp-25A5 185648   NP_500322 31
A.thaliana CYP711A1 817157   NP_565617 30
C.elegans cyp-25A6 187059   NP_500512 30

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta