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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMAD3, SMAD family member 3
Sequence ID:NM_001145102
RefSeqGene ID:NG_011990
Entrez Gene ID:4088
Ensembl ID:ENSG00000166949

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q22.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 67358609 - 67482922

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6094328Full LengthBC050743SMAD family member 3
2961412IncompleteBC000414SMAD family member 3
2961412IncompleteBC007496SMAD family member 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005893  

Protein Infomation

NM_001145102 NP_001138574    
NM_001145103 NP_001138575    
NM_001145104 NP_001138576    
NM_005902 NP_005893 P84022 MH1

Related Sequences

U76622 AAB18967 P84022
U68019 AAB80960 P84022
AF151027 AAF36113 Q9P0T0
BC050743 AAH50743 P84022
EU446487 ABZ92016  
AB209616 BAD92853 Q59F45
AK290881 BAF83570 P84022
AK313812 BAG36548 Q6I9W9
AK298139 BAH12731 P84022
AK300614 BAH13315 B7Z6M9
AK301348 BAH13461 B7Z725
AK316017 BAH14388 P84022
CR457386 CAG33667 Q6I9W9
CR749287 CAH18142 Q68DS8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMAD3 NP_005893 M.musculus Smad3 17127 Gene Info NP_058049 100
R.norvegicus Smad3 25631   NP_037227 100
D.melanogaster Smox 31738   NP_511079 71
A.gambiae AgaP_AGAP009777 1279189   XP_318870 68

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta