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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AFG3L2, AFG3 ATPase family member 3-like 2 (S. cerevisiae)
Sequence ID:NM_006796
RefSeqGene ID:NG_023361
Entrez Gene ID:10939
Ensembl ID:ENSG00000141385

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:18p11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 12342045 - 12343942

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6169804Full LengthBC065016AFG3 ATPase family gene 3-like 2 (yeast)
4840336IncompleteBC024282AFG3 ATPase family gene 3-like 2 (yeast)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006787  

Protein Infomation

NM_006796 NP_006787 Q9Y4W6 AAA

Related Sequences

BC024282 AAH24282 Q8TA92
BC065016 AAH65016 Q9Y4W6
Y18314 CAB48398 Q9Y4W6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AFG3L2 NP_006787 R.norvegicus Afg3l2 307350   NP_001128336 94
M.musculus Afg3l2 69597 Gene Info NP_081406 93
D.melanogaster CG6512 39922   NP_730248 69
A.gambiae AgaP_AGAP006949 1270135   XP_308807 68
C.elegans spg-7 171915   NP_491165 64
S.pombe SPBC543.09 2541079   NP_596797 58
S.cerevisiae YTA12 855114   NP_013807 57
A.thaliana ftsh3 817456   NP_850129 56
A.thaliana ftsh10 837265   NP_172231 56
N.crassa NCU01479 3872904   XP_956756 54
P.falciparum PF11_0203 810750   XP_001347874 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)