Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SQSTM1, Sequestosome 1
Sequence ID:NM_001142298
NM_003900
NM_001142299
RefSeqGene ID:NG_011342
Entrez Gene ID:8878
Ensembl ID:ENSG00000161011

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PAGET DISEASE OF BONETNFRSF11A
TNFRSF11A

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 179248122 - 179264254

 Exon Info From UCSC:
NM_001142298
NM_003900
NM_001142299

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2906264Full LengthBC003139sequestosome 1
3535436Full LengthBC001874sequestosome 1
4298142Full LengthBC017222sequestosome 1
5091391Full LengthBC019111sequestosome 1
3029863IncompleteBC005857sequestosome 1
3449348IncompleteBC000951sequestosome 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003891  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001142298 NP_001135770    
NM_001142299 NP_001135771    
NM_003900 NP_003891 Q13501 PB1
ZZ

Related Sequences

 
mRNAGenPeptSwissProt
U41806 AAA93299 Q13501
U46751 AAC52070 Q13501
BC000951 AAH00951 Q13501
BC001874 AAH01874 Q13501
BC003139 AAH03139 Q13501
BC017222 AAH17222 Q13501
BC019111 AAH19111 Q13501
DQ892878 ABM83804  
EU176717 ABW03518  
AK312451 BAG35358 Q13501
AK098077 BAG53577 Q13501
AK293509 BAG56993 B4DE82
AK304877 BAG65614 B4E3V2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SQSTM1 NP_003891 R.norvegicus Sqstm1 113894   NP_787037 92
M.musculus Sqstm1 18412 Gene Info NP_035148 91
A.gambiae AgaP_AGAP009928 1279342   XP_319049 31
D.melanogaster ref(2)P 35246   NP_476700 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)