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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GRK1, G protein-coupled receptor kinase 1
Sequence ID:NM_002929
Entrez Gene ID:6011
Ensembl ID:ENSG00000185974

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
OGUCHI DISEASE-1SAG

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 114437447 - 114440708

NM_002929 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
4807114321596114322399
808935114324001114324128
9361093114325813114325970
10941177114426046114426129
11781302114434191114434315
13031504114435856114436057
15051961114438040114438496
19622099114438498114438635

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9056757Full LengthBC140945G protein-coupled receptor kinase 1

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002929 NP_002920 Q15835 EC 2.7.11.14 Pkinase
RGS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U63973 AAB05929 Q15835 EC 2.7.11.14
L77503 AAG50439 Q15835 EC 2.7.11.14
BC140945 AAI40946 B9EIS4  
AK289912 BAF82601 Q15835 EC 2.7.11.14

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GRK1 NP_002920 M.musculus Grk1 24013 Gene Info NP_036011 86
R.norvegicus Grk1 81760   NP_112358 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta