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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LEPRE1, leucine proline-enriched proteoglycan (leprecan) 1
Sequence ID:NM_001146289
NM_001243246
NM_022356
RefSeqGene ID:NG_008123
Entrez Gene ID:64175
Ensembl ID:ENSG00000117385

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
OSTEOGENESIS IMPERFECTA, TYPE VIII 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 43212044 - 43232693

 Exon Info From UCSC:
NM_001146289
NM_022356

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4521167Full LengthBC108311leucine proline-enriched proteoglycan (leprecan) 1
4395073IncompleteBC015309leucine proline-enriched proteoglycan (leprecan) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_071751  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001146289 NP_001139761      
NM_001243246 NP_001230175      
NM_022356 NP_071751 Q32P28 EC 1.14.11.7 2OG-FeII_Oxy

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF097431 AAG31018 Q32P28 EC 1.14.11.7
AF097432 AAG31019 Q32P28 EC 1.14.11.7
BC015309 AAH15309 Q32P28 EC 1.14.11.7
BC108311 AAI08312 Q32P28 EC 1.14.11.7
BT007039 AAP35688 Q32P28 EC 1.14.11.7
AK025841 BAB15256 Q32P28 EC 1.14.11.7
AK027648 BAB55264 Q32P28 EC 1.14.11.7
AK027680 BAB55291 Q32P28 EC 1.14.11.7
AK027697 BAB55305 Q32P28 EC 1.14.11.7
AK075418 BAC11608 Q32P28 EC 1.14.11.7
AK297980 BAG60290 B4DNM8  
AK300210 BAG61980 B4DTG8  
CR749690 CAH18474 Q68CW0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LEPRE1 NP_071751 R.norvegicus Lepre1 114200   NP_446119 89
M.musculus Lepre1 56401 Gene Info NP_062757 88

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)