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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GBA, Glucosidase, beta, acid
Sequence ID:NR_002188
RefSeqGene ID:NG_009783
Entrez Gene ID:2629
Ensembl ID:ENSG00000177628

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DEMENTIA, LEWY BODYSNCA
SNCB
GAUCHER DISEASE, PERINATAL LETHAL 
GAUCHER DISEASE, TYPE I 
GAUCHER DISEASE, TYPE II 
GAUCHER DISEASE, TYPE III 
GAUCHER DISEASE, TYPE IIIC 
PARKINSON DISEASEADH1C
DBH
DRD4
FGF20
MAPT
NDUFV2
NR4A2
SNCAIP
TBP
UCHL1

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 155184064 - 155188796


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2899915Full LengthBC003356glucosidase, beta; acid (includes glucosylceramidase)

Protein Infomation

Related Sequences

 
mRNAGenPeptSwissProt
AK295259 BAG58248 B4DHT6
AK297653 BAG60020 B4DMV8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GBA NP_000148 M.musculus Gba 14466 Gene Info NP_001070879 87
C.elegans Y4C6B.6 177314   NP_500785 44
C.elegans F11E6.1 178535   NP_503119 43
C.elegans glucosylceramidase 173574   NP_001040750 41
A.gambiae AgaP_AGAP001649 1281524   XP_321447 39
C.elegans glucosylceramidase 183155   NP_494208 39
D.melanogaster CG31414 318721   NP_001097888 36
D.melanogaster CG31148 42796   NP_651172 36
N.crassa NCU04395 3873626   XP_957472 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)