Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPCS2, signal peptidase complex subunit 2 homolog (S. cerevisiae)
Sequence ID:NM_014752
Entrez Gene ID:9789
Ensembl ID:ENSG00000118363

Database Links

UniGeneEntrez GeneEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.4Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 74660310 - 74688779

NM_014752 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2967488Full LengthBC008063signal peptidase complex subunit 2 homolog (S. cerevisiae)
3954096Full LengthBC082231signal peptidase complex subunit 2 homolog (S. cerevisiae)
4521501Full LengthBC106066signal peptidase complex subunit 2 homolog (S. cerevisiae)
4656138Full LengthBC070276signal peptidase complex subunit 2 homolog (S. cerevisiae)
6092500Full LengthBC064957signal peptidase complex subunit 2 homolog (S. cerevisiae)
5303403IncompleteBC067821signal peptidase complex subunit 2 homolog (S. cerevisiae)

Protein Infomation

NM_014752 NP_055567 Q15005 SPC25

Related Sequences

BC008063 AAH08063 Q15005
BC064957 AAH64957 Q15005
BC070276 AAH70276 Q15005
BC082231 AAH82231 Q15005
BC106066 AAI06067 Q15005
HQ448126 ADQ32607  
D14658 BAA03492 Q15005
AK293128 BAG56680 B4DDB9
CR542233 CAG47029 Q15005
CR542243 CAG47039 Q15005

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPCS2 NP_055567 M.musculus Spcs2 66624 Gene Info NP_079944 96
R.norvegicus Spcs2 293142   XP_214994 95
A.gambiae AgaP_AGAP011842 1280809   XP_320676 48
C.elegans Y37D8A.10 176703   NP_499676 42
D.melanogaster Spase25 32095   NP_572723 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)