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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SIRT3, Sirtuin 3
Sequence ID:NM_012239
Entrez Gene ID:23410
Ensembl ID:ENSG00000142082

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 216142 - 236416

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823471Full LengthBC001042sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036371  NP_001017524  

Protein Infomation

NM_001017524 NP_001017524   SIR2
NM_012239 NP_036371 Q9NTG7 SIR2

Related Sequences

AF083108 AAD40851 Q9NTG7
BC001042 AAH01042 Q9NTG7
AK298572 BAH12816 B7Z580
AK299009 BAH12927 B7Z5J1
AK299438 BAH13032 Q9NTG7
AK301558 BAH13513 B7Z777
AK301979 BAH13600 B7Z7G4
AK316175 BAH14546 B7ZA60
AL137276 CAB70674 Q9NTG7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SIRT3 NP_036371 R.norvegicus Sirt3 293615   NP_001099783 86
M.musculus Sirt3 64384 Gene Info NP_001171275 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)