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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LDLR, low density lipoprotein receptor
Sequence ID:NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
RefSeqGene ID:NG_009060
Entrez Gene ID:3949
Ensembl ID:ENSG00000130164

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CORONARY ARTERY DISEASE IN FAMILIAL HYPERCHOLESTEROLEMIA, PROTECTION AGAINSTABCA1
APOA2
EPHX2
GHR
GHR
GHR
ITIH4
PPP1R17

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 11200153 - 11242488


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542845Full LengthBC014514low density lipoprotein receptor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000518  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000527 NP_000518 P01130 EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA
NM_001195798 NP_001182727    
NM_001195799 NP_001182728    
NM_001195800 NP_001182729    
NM_001195802 NP_001182731    
NM_001195803 NP_001182732    

Related Sequences

 
mRNAGenPeptSwissProt
M28219 AAA59509  
S40543 AAB22609 Q16479
S70123 AAB30338  
BC014514 AAH14514 P01130
AY114155 AAM56036 P01130
BT007361 AAP36025 P01130
DQ893879 ABM84805  
AB209409 BAD92646 Q59FQ1
AK295612 BAG58495 B4DII3
AK296312 BAG59010 P01130
AK299038 BAG61112 P01130
AK300313 BAG62065 P01130

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LDLR NP_000518 M.musculus Ldlr 16835 Gene Info NP_034830 79
R.norvegicus Ldlr 300438   NP_786938 77

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta