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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DOT1L, DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Sequence ID:NM_032482
RefSeqGene ID:NG_029793
Entrez Gene ID:84444
Ensembl ID:ENSG00000104885

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 2210698 - 2230007

 Exon Info From UCSC:
NM_032482

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3865769IncompleteBC032803DOT1-like, histone H3 methyltransferase (S. cerevisiae)
100062384BC156103DOT1-like, histone H3 methyltransferase (S. cerevisiae)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_032482 NP_115871    

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC156103 AAI56104    
AF509504 AAM88322 Q8TEK3 EC 2.1.1.43
AB058717 BAB47443 Q8TEK3 EC 2.1.1.43
AK074120 BAB84946 Q8TEK3 EC 2.1.1.43

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DOT1L NP_115871 M.musculus Dot1l 208266 Gene Info NP_955354 85
R.norvegicus Dot1l 362831   NP_001102203 85

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)