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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K12, mitogen-activated protein kinase kinase kinase 12
Sequence ID:NM_001193511
NM_006301
Entrez Gene ID:7786
Ensembl ID:ENSG00000139625

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 53874273 - 53880512

 Exon Info From UCSC:
NM_001193511
NM_006301

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4824512Full LengthBC050050mitogen-activated protein kinase kinase kinase 12
5532846IncompleteBC037585mitogen-activated protein kinase kinase kinase 12

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006292  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001193511 NP_001180440      
NM_006301 NP_006292 Q12852 EC 2.7.11.25 Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U07358 AAA67343 Q12852 EC 2.7.11.25
BC050050 AAH50050 Q12852 EC 2.7.11.25
AB209453 BAD92690 Q59FK7  
AK094195 BAG52841 B3KSS9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K12 NP_001180440 M.musculus Map3k12 26404 Gene Info NP_033608 96
R.norvegicus Map3k12 25579   NP_037187 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta